Category: Genomics - Page 2

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12
Mar
2025

Epigenetics In Human Reproduction

Louisa Ghevaert was delighted to attend the Nuffield Council on Bioethics workshop “Epigenetics in human reproduction” in central London on 11 March 2025. This event looked at the use and implications of epigenetics in human reproduction. It considered the inter-relationships between the reproductive environment, the epigenome, long-term health and assisted reproductive technologies. It went on to explore current and future scientific applications, ethical, legal and social implications. In doing so, it explored all sorts of important and complex questions and issues. How do you measure or control the environment? How effective may an intervention be and at what stage to optimise health, pregnancy and birth? How do you account for epigenetic responses (mechanisms that regulate gene expression without changing the DNA sequence) that differ between people? How reliable is epigenetic testing? How can you provide effective messaging? How do you address these issues from a policy perspective?

03
Mar
2025

Can Genetics Impact Fertility?

A medical study in the last year has found that genetic defects affect half of all infertility cases.(1) This brings into focus the significance of genetics for family building purposes in terms of fertility, conception, pregnancy and birth (and not just from a disease and health perspective). This can make it important to consider a range of genetic, medical and legal questions with geneticists, clinical and legal professionals. Should I undergo genetic testing to see if I might have difficulties with pregnancy or pass a genetic disorder on to my child? Should I undergo genetic counselling before conception? Should I get my embryos genetically screened before implantation? Should I undergo fertility preservation treatment? How can I maximise my chances of successful conception, birth or family completion? How can I maximise my prospects of having a genetically related child? Should I undergo prenatal testing? How can I legally protect my stored eggs, sperm and embryos? How can I successfully navigate fertility treatment law in the UK? What will happen to my stored eggs, sperm or embryos and my genetic legacy if I die?

27
Jan
2025

Genetic Testing, Political Uncertainty & Citizenship: Family Law In Focus

As we start 2025, the evolving realities of direct-to-consumer DNA tests, political uncertainty and demand for foreign citizenship are increasingly calls to action. As people seek to understand and address these challenges it can create complex inter-related personal and legal questions. Such questions are increasingly drawing together and necessitating solutions that require specialist family law expertise. Successfully navigating a path through these choppy waters can require expert management and bespoke family law strategies to address the implications of genetic testing, legal and biological parentage, an application for a Declaration of Parentage and rectification of a birth certificate.

04
Nov
2024

Newborn Genome Sequencing At Birth: The Generation Study Progress Update

Louisa was pleased to attend Progress Educational Trust's event "Whole Genome Sequencing at Birth: Implementing The Generation Study" on 23 October 2024. This event provided a progress update on The Generation Study, which is an NHS embedded research study undertaking whole genome sequencing of 100,000 newborn babies at different hospitals across England. The Generation Study's aim is to better inform future decisions about using whole genome sequencing to support newborn screening and understand whether this can improve our ability to diagnose and accelerate access to treatment for rare genetic conditions.

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