Covid-19 is an effective mass disrupter with serious global morbidity and mortality implications. It is, however, just part of a wider complex picture that is rapidly evolving around us. With the continual development of powerful transformative gene-editing tools and scientific and digital technology we increasingly have the capacity to digitally programme, enhance and re-structure our genome and life itself. There is therefore an urgent need to implement intelligent genomic and fertility law reform and develop new policies and practices to deal with fallout from the Covid-19 global pandemic, changing geopolitics, evolving biopolitics, declining fertility levels and rapid intersection of genomics, digital, AI and assisted reproductive technology.